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August 12, 2010

Hormonal Contraceptives are Less Effective in Obese/Overweight Women

A systematic review of results reported online has concluded that hormonal contraceptives (such as skin patches, vaginal rings, implants, pills, and injections) may not be as effective in overweight and obese women.

With obesity rates increasing worldwide every year, it is important that these findings be shared with the public.

The results from seven studies on 39,531 women on the success of hormonal contraceptives were examined and the results were varied among the different methods of birth control.  Some methods such as the birth control pill were less effective at preventing pregnancy in the obese and overweight women who used a hormonal contraceptive.

Body mass index, or BMI, played a large role in the effectiveness of the birth control pill.  Women with a BMI higher than 25 (classified as overweight), were more likely to get pregnant while using the pill than women with a BMI under 25.

Body weight, on the other hand, was the factor among women using the skin patch, vaginal ring, implant, or injection.  The body weight due to fat on the body determined the pregnancy risk among women using contraception.  Overweight and obese women using the skin patch, progestin implant, and vaginal ring were more likely to get pregnant than women of normal weight using these forms of contraception.  Curiously enough, the effectiveness of the hormonal injection was not affected by BMI or body weight.  One possible reason for the decreased effectiveness of the skin patch is simply that there is a higher density of fat cells in areas where the patch is to be placed.  The fat cells in the way of the blood stream can absorb and store the hormones preventing them from reaching the blood stream.

The exact reason why overweight and obese women are at a greater risk of pregnancy while using hormonal contraceptives is unknown.  Although several theories imply that it has something to do with specific biological factors.

Liver Enzymes – overweight women can experience an increased regulation of liver metabolism.  These higher levels of enzymes can help break down the hormones in oral contraceptives.  Heavier women have a greater circulating blood volume and body mass therefore there is more tissue for blood to circulate though. The chance that enzymes will break down the hormones in contraception is faster therefore the levels of circulating hormones can be decreased.

Hormone Storage – Hormones like estrogen and progestin that are found in birth control are stored in body fat.  The more fat cells on a woman, the greater her chances of the hormones becoming stored in her fat rather than flowing into her bloodstream.

Pharmapassport.com, a Canadian Internet-based pharmacy intermediary (license #BC X23), provides customers with low prices and long-term prescriptions drugs. All Canadian prescriptions are filled by a professionally registered pharmacist. For more information on how to order Canada drugs safely and securely call 1-866-293-3904 or visit http://www.pharmapassport.com/ – a trusted and reliable Canadian online pharmacy that has filled over 1 million prescriptions.

January 28, 2010

8 Breast Cancer Myths

Breast cancer is a touchy topic but it is important for you to know the facts about it. There are many rumors about your susceptibility of getting cancer and many of them aren’t true. Everyone should be aware about breast cancer. Here are the facts:

Myth: You’re more likely to get breast cancer if you are older


The truth is that although the risk of breast cancer increases as we become older, breast cancer is likely to occur at any age. One woman in 231 younger than 39 years of age will get breast cancer. Between the ages of 40 and 59, the risk becomes one in 25 women. From the age of 60 – 79, the risk is one in 15 women. If you live to the age of 90, your risk of getting breast cancer over an entire lifetime is one in 7.

Myth: If you have greater risk factors for breast cancer, you are more likely to get it
The truth is that getting breast cancer is not certain. Even if you have a stronger risk factor such as a breast cancer gene it is not certain that you will develop it. Out of the women with the inherited breast cancer gene, between 40 and 80% will develop cancer over their lifetime. 20-60% will not.

Myth: If breast cancer doesn’t run in your genes you won’t get it
The truth is that almost 80% of women who get breast cancer have no known family history of breast cancer. The biggest single risk factor is aging. For women who do have family history of breast cancer, the risk may go up, or not at all. Talk to your doctor about your family history if you are worried.

Myth: You can only get breast cancer if it comes from your mothers side of the family

The truth is that a history of breast cancer from either side of your family will affect your risk equally. Half of your genes come from your mother, and half of your genes come from your father. A man with a breast cancer gene abnormality is less likely to get breast cancer than a woman with a similar gene. If you would like to find out about your fathers family history, look at both the women and the men in his family.

Myth: Antiperspirants cause breast cancer

The truth is that there is no solid evidence that the ingredients in antiperspirants affect your risk of breast cancer. It is possible that certain products containing carcinogens can contribute to a an already existing breast cancer development, but antiperspirants alone will have no effect on your risk of developing cancer.

Myth: Birth control pills cause breast cancer
The truth is that there is no relationship between modern day estrogen and progesterone birth control pills and a risk of developing breast cancer. One study did show that there is a very small increase in the risk of developing breast cancer by using birth control, but after time the slight increase began to decrease. After 10 years birth control pills did not show any association with breast cancer development. In fact, birth control pills have been found to reduce certain cancer risks such as ovarian and endometrial cancer.

Myth: I cannot change that fact that I am at risk of developing breast cancer
The truth is there are things you can do to decrease your risk of developing breast cancer if you have the breast cancer gene. Lifestyle changes are the most effective way to reduce your risk. Minimize your alcohol intake, don’t smoke, and exercise regularly to improve your health and reduce your risk. Remember to have regular breast exams and mammograms to watch for cancerous lumps. There are also medicinal options for women with a high risk of breast cancer. Talk to your doctor about your risk of developing breast cancer.

Myth: Eating foods high in fat causes breast cancer

The truth is that there is no definite relationship between eating fatty foods and developing breast cancer. Avoiding fatty foods, however, will lower your cholesterol levels, make room in your diet for healthier alternatives, and help you control your weight. Being overweight does increase your risk of developing breast cancer. If you are overweight already, cutting back on fatty foods is a good idea.

Pharmapassport.com, a Canadian Internet-based pharmacy intermediary (license #BC X23), provides customers with low prices and long-term prescriptions drugs. All Canadian prescriptions are filled by a professionally registered pharmacist. For more information on how to order Canada drugs safely and securely call 1-866-293-3904 or visit http://www.pharmapassport.com/ – a trusted and reliable Canadian online pharmacy that has filled over 1 million prescriptions.