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Promacta 
Description
Generic Name: eltrombopag
Drug Class: thrombopoietin receptor agonist
Promacta Details
Promacta is an oral prescription drug used to treat thrombocytopenia among adults and pediatric patients 1 year and above with chronic immune idiopathic thrombocytopenia whose response to corticosteroids, immunoglobulins, and splenectomy is insufficient. It also treats thrombocytopenia among patients with chronic hepatitis C. This is also prescribed for patients with severe aplastic anemia whose response to immunosuppressive therapy is insufficient.
Promacta Side Effects
Mild & Common Side Effects:
-Headache
-Nausea
-Diarrhea
-Muscle pain
-Tingling
-Numbness
Severe Side Effects:
-Vision changes
-Sudden shortness of breath
-Chest pain
-Coughing up blood
-Sudden dizziness
-Fainting
-Weakness on one side of the body
-Trouble speaking
Note that this is not a full/complete list of the side effects of Promacta.
Promacta Warnings
Do not take this prescription drug if you have a known allergy to eltrombopag or any inactive ingredients it may contain. If you experience severe or persistent adverse reactions, such as trouble breathing, swelling of the face and neck, severe dizziness, swollen lymph nodes, hives/itchiness, and skin rashes, discontinue medication and talk to your doctor or any health care professional.
This medication may be contraindicated for people with a history of blood clots or any clotting problems, blood disorders, hepatic impairment, and eye problems. Also, due to possible drug interactions, you should discuss all the prescription medications, nonprescription medications, vitamins or mineral supplements, and herbal products you are taking.
Although this drug addresses bleeding, you should take caution to prevent bleeding. You must practice safety caution when using sharp objects, such as razors, knives, and nail cutters. You should also try to avoid contact sports or any similar activities that can cause bruising and bleeding.
Pregnant moms must avoid taking this medication as it can cause harm to unborn babies. Women are also being advised not to get pregnant while on this therapy. For breastfeeding moms, it is unknown if it can pass into the breastmilk, but because of the risks, it is not recommended.
Promacta Dosage Forms
This is available in Promacta 50 mg and 25 mg tablets.
Promacta Mechanism of Action
It interacts with the transmembrane domain of the human TPO-receptor, which initiates the signaling cascades in order to induce the proliferation and differentiation of megakaryocytes coming from the bone marrow progenitor cells. This, then, leads to an elevation in the number of platelets and the prevention of the risk of bleeding.
How to Take Promacta
Before taking this medication, it is necessary to read the drug information leaflet or medication guide given by a healthcare professional.
This is usually prescribed once a day and should only be taken by mouth. You may take it with or without a meal that is low in calcium. Swallow the oral tablet entirely and drink fluids right after. Crushing or chewing this oral medication is not recommended.
Make a dosing schedule. It should be taken 2 hours prior or 4 hours after taking any products that contain aluminum, magnesium, and calcium-rich foods. Do not increase or decrease your Promacta dose. You should not take this oral drug more frequently than advised. Additionally, do not discontinue this drug abruptly as it can increase the risk of bleeding.
What is The Price of Promacta?
You may see the list of prices on this page. To get the best deals, purchase your prescription drugs from Pharma Passport.
Frequently Asked Questions (FAQs)
What is Promacta used for?
Promacta (eltrombopag) is being used to treat low platelet levels. Physicians prescribe Promacta for ITP, chronic hepatitis C, and severe aplastic anemia.
When is the best time to take Promacta?
This drug is usually prescribed one hour before or two hours after eating. It is best to take it at the same time each day.
Does Promacta cause stomach problems?
Taking this oral medication can cause nausea and diarrhea. Although these are common, if these adverse effects persist, you must report them to your healthcare provider.
What happens when you stop taking Promacta?
When you stop Promacta abruptly and without the advice of your doctor, bleeding or easy bruising may occur. You must not discontinue this drug abruptly.
Are Nplate and Promacta the same?
Nplate vs Promacta – Both medications are classified as thrombopoietin receptor agonists. Even so, these drugs contain different active ingredients.
Is Promacta over the counter?
This product is a prescription drug. Please present a valid prescription when buying this medication.