Order Climara Patch Online | Pharmapassport
Join our Mailing list

Follow Us

Call us on Toll Free : +1-866-293-3904
Fax us on Toll Free : +1-877-247-9918

  • No products in the cart.
Generic selectors
Exact matches only
Search in title
Search in content
Search in posts
Search in pages
  • No products in the cart.
Generic selectors
Exact matches only
Search in title
Search in content
Search in posts
Search in pages
  • No products in the cart.

Are you Looking to Buy Climara Patch (Estradiol) from Pharmapassport.

We don't sell this generic-version medication.

( Top Brand Option )

Price Match See Alternative Pricing below for savings

Buy Brand Climara Patch

Prescription Prescription Required
Formulation : Patch
Drug Name Dosage Quantity Price Buy Now
Climara Patch 25mcg 4 $43.43 Add To Cart
Climara Patch 25mcg 8 $61.20 Add To Cart
Climara Patch 50mcg 4 $44.44 Add To Cart
Climara Patch 50mcg 8 $77.97 Add To Cart
Climara Patch 50mcg 12 $111.07 Add To Cart
Climara Patch 75mcg 12 $88.00 Add To Cart
Climara Patch 75mcg 24 $160.15 Add To Cart
Climara Patch 100mcg 12 $108.07 Add To Cart
Climara Patch
Dosage: 25mcg
Quantity: 4
Price: $43.43
Climara Patch
Dosage: 25mcg
Quantity: 8
Price: $61.20
Climara Patch
Dosage: 50mcg
Quantity: 4
Price: $44.44
Climara Patch
Dosage: 50mcg
Quantity: 8
Price: $77.97
Climara Patch
Dosage: 50mcg
Quantity: 12
Price: $111.07
Climara Patch
Dosage: 75mcg
Quantity: 12
Price: $88.00
Climara Patch
Dosage: 75mcg
Quantity: 24
Price: $160.15
Climara Patch
Dosage: 100mcg
Quantity: 12
Price: $108.07


Generic Name: estradiol 

Drug Class: estrogen derivative 


Climara is a transdermal prescription patch used to treat moderate to severe vasomotor symptoms and symptoms of vulvar and vaginal atrophy secondary to menopause. It can also prevent postmenopausal osteoporosis. This is also indicated to treat hypoestrogenism due to primary ovarian failure, hypogonadism, and castration. 

Climara Dosage 

This is available in Climara 25 mcg, 50 mcg, 75 mcg, and 100 mg transdermal systems. 

Climara Mechanism of Action 

This works as the principal intracellular estrogen and is known to be more potent than estrone and estriol. It then regulates the pituitary secretion of follicle-stimulating hormones, luteinizing hormones, and gonadotropins via a negative feedback mechanism. It can also reduce the elevated levels of hormones among postmenopausal women. 

How to Use Climara Patch 

Before using Climara, it is necessary to read the drug information or patient information leaflet, or medication guide given by a healthcare professional. You must not use any medication unless you have understood the uses and directions. For more medical advice or information, consult your doctor or pharmacist. 

This patch is worn continuously and should be replaced every seven days. Make a schedule so you will not forget to remove and replace your patch. Do not increase/decrease your dosage or use the patch longer than intended. 

Step-by-step Guide on how to use Climara Patch. 

  1. Open the packaging by tearing it from the notch. Avoid using scissors.
  2. Remove the thick plastic adhesive-attached clear plastic film.
  3. Apply the transdermal patch to a clean and dry surface in your lower abdomen or buttocks. The patch should be placed in different areas every week. Do not put it near or in the breast area, and do not touch the sticky part of the patch. 
  4. Press the patch firmly into the skin and rub the edges to ensure that it will stay in place.
  5. After 7 days, remove the patch by detaching it slowly from the area. If there are remaining residues, wait for around 15 mins before you gently rub the area with an oil-based lotion or cream.
  6. Dispose of the patch by folding the sticky side together. Then, throw it properly.

Climara Side Effects 

Mild & Common Side Effects: 

-Redness or irritation in the application area 

-Nausea and vomiting 



-Abdominal pain 

-Breast tenderness 

-Weight changes 


-Skin discoloration 

-Increased facial hair

Severe Side Effects: 

-Mental or mood changes 

-Unusual vaginal bleeding 

-Increased vaginal irritation or discharge 

-Persistent vomiting 

-Severe abdominal pain 

-Increased thirst and urination 

-Blood clot formation 

-Chest pain 

-Weakness on one side of the body 

-Sudden dizziness 

-Trouble breathing

Note that this is not a full/complete list of the side effects of Climara.

If you experience severe or persistent adverse reactions, discontinue medication and call your doctor or healthcare professional.

Warnings and Precautions 

Do not use Climara Patch if you have a known allergy to estradiol or any inactive ingredients the tablet may contain. Always be watchful for any signs of serious allergic reactions, including trouble breathing, swelling of the face and neck, severe dizziness, swollen lymph nodes, hives/itchiness, and skin rashes. Stop using this oral medication and seek emergency medical treatment right away if this happens.

Climara may be contraindicated for people with a history of breast cancer, ovarian cancer, cancer of the uterus, vaginal bleeding of unknown cause, blood clots, heart attack or any heart disease, kidney disease, liver disease, blood clotting disorders, angioedema, diabetes, high blood pressure, high levels of cholesterol and triglyceride, obesity, hypothyroidism, hypoparathyroidism, mineral imbalances, lupus, gallbladder disease, seizure, asthma, migraine, porphyria, uterus problems, any mental or mood disorders. Also, due to possible drug interactions, you should discuss all the prescription medications, nonprescription medications, supplements, and herbal products you are taking.

Estradiol can possibly increase the risk of blood clots. Tell your healthcare provider if you will be in a certain position for a long period, such as going through surgery or going on a long-haul flight. You may have to discontinue Climara for a while under certain circumstances. Additionally, you should also avoid smoking or using tobacco, for they contain substances that can also increase the risk of blood clots.

This transdermal system can also make you more sensitive to sun exposure. It can cause dark, blotchy patches on the face, called melasma. While using this drug, limit your exposure to the sun. You should also avoid indoor tanning and always wear protective clothing when going out.

If you go through an MRI procedure, tell your physician or a radiologist that you have a patch on. This may contain metals that can cause serious burns during an MRI test. You may be asked to remove the patch before the procedure and apply a new patch after.

This type of medication should not be used during pregnancy and while breastfeeding. It is essential to discuss all the possible risks with a healthcare provider. 

Frequently Asked Questions (FAQs) 

Is Climara estrogen-only? 

This prescription patch only contains estrogen. This is indicated to replace the estrogen lost during menopause. 

Is Climara Patch bioidentical? 

This transdermal system falls under bioidentical hormone therapy. This patch is derived from plants and is chemically processed and altered in a laboratory. 

Does Climara cause weight gain? 

The link between Climara Patch and weight gain is due to the fluid retention that can be caused by estradiol. Other common side effects are bloating, stomach cramps, nausea, and vomiting. 

What is the difference between Climara Pro and Combipatch? 

Climara Pro vs Combipatch – Both medications are used to treat menopausal symptoms. However, while Combipatch is used twice weekly, Climara is only replaced once a week. 

Is Vivelle Dot the same as Climara? 

Climara vs Vivelle – Both transdermal patches are used to address menopausal symptoms. However, Climara transdermal system can also prevent postmenopausal osteoporosis. 

How much does Climara cost? 

Click here to see our prices on Climara Patch. Get the best deals when you order your prescription drugs from PharmaPassport. 

Do I need a prescription for Climara? 

This product is a prescription drug. You need to have a valid prescription before purchasing from any pharmacy. 

Additional information

Scientific Name:





25mcg, 50mcg, 75mcg, 100mcg

Quantities Available:

4, 8, 12, 24

The contents on this page was provided by third parties to Pharmapassport.com. The information for Climara Patch (Estradiol) is not intended to substitute for qualified health care professional's advice. Please consult with your doctor if you have any questions or require medical advice.

Generic selectors
Exact matches only
Search in title
Search in content
Search in posts
Search in pages

We regret to inform you that Pharmapassport is currently experiencing disruptions in service due to a power outage. Currently, the call center, email and chat functions of our website may be unavailable. Our teams have been dispatched to tackle this issue head-on and service should hopefully resume momentarily.