Januvia (sitagliptin) is an oral prescription given as an adjunct to proper diet and exercise to manage high blood sugar levels or improve glycemic control among people with type 2 diabetes mellitus. Januvia also helps prevent complications of diabetes, such as nerve problems, blindness, sexual dysfunctions, kidney problems, stroke, and heart attack.
Januvia should not be used for type 1 diabetes and diabetic ketoacidosis.
This is available in Januvia 100 mg, 50 mg, and 25 mg tablets.
Januvia Mechanism of Action
This anti-diabetic medication slows down the inactivation of incretin hormones. Incretin hormones include glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), responsible for increasing insulin synthesis and release from the pancreatic beta cells. It also decreases glucagon levels in the system in a glucose-dependent manner.
How to Use Januvia
Before taking this medication, it is necessary to read the information leaflet or medication guide given by a healthcare professional. You must not take any medication unless you have understood all the information regarding it. Ask your doctor or pharmacist for further medical advice or additional details.
This tablet is only meant to be taken by mouth. You may administer your dose with a meal or on an empty stomach. Swallow the tablet whole and drink fluids right after. It is not recommended to cut, crush, or chew this type of medication. You should also comply with the recommended diet, and you must exercise regularly to get the full benefits of this drug.
Establish a schedule for your doses to avoid missing them. This is usually prescribed once daily and at the same time each day. If you miss your medication, take it right away, except if it is almost time for your next scheduled dose. Do not increase or decrease your medication dosage and alter your frequency as they are based on your health condition, kidney function, and response to treatment. You should also keep taking this diabetes drug. Stopping this medication for a while or abruptly can result in worsening conditions.
Side Effects of Januvia
Mild & Common Side Effects:
Severe Side Effects:
-Low blood sugar or hypoglycemia
-High blood sugar or hyperglycemia
-Changes in urine output
-Unusual skin blisters
-Heart failure (shortness of breath, sudden weight gain, swelling of the lower extremities, unusual tiredness)
-Symptoms of pancreatitis (severe abdominal pain, persistent nausea & vomiting, loss of appetite)
Note that this is not a full/complete list of Januvia’s side effects.
If you experience severe or persistent adverse reactions, discontinue medication and consult your doctor or any healthcare professional.
Precautions / Warnings
Do not take this anti glycemic agent if you have a known allergy to sitagliptin or any inactive ingredients each tablet may contain. Watch out for some signs of a severe allergic reaction, including difficulty breathing, swelling of the face and neck, severe dizziness, hives/itchiness, and skin rashes. If this happens, immediately stop taking this oral medication and seek emergency medical attention.
Certain diseases or disorders may directly affect how your body will respond to the treatment. Disclose the entire medical history to the doctor. This must include any history of pancreatitis, gallstones, kidney disease, and heart failure. Because of potential drug interactions, you should discuss all herbal products, prescription drugs, OTC drugs, and supplements you are taking.
Your risk of hypoglycemia may increase if you consume alcohol. Alcohol can also trigger side effects, such as dizziness, drowsiness, and blurred vision. Avoid or limit the consumption of alcoholic beverages while on this medication. You should also observe caution when doing activities that need clear vision or alertness, including driving and operating machinery.
Your diabetes could possibly get worse once you become pregnant. Discuss the possible risks of taking this diabetes medication throughout pregnancy. For breastfeeding moms, it is still unknown if this drug can pass into breast milk. You may take this medication only if clearly needed.
Frequently Asked Questions (FAQs)
1. How does Januvia work?
This medication works by increasing and prolonging active incretin levels.
2. Is Januvia medication safe for the kidneys?
This anti-diabetic medication is not directly linked to kidney problems.
3. Can Januvia be given to people with pancreatitis?
This medication may aggravate pancreatitis and should be avoided.
4. What is the best time to take Januvia?
You may take this drug in the morning or the evening.
5. How much does Januvia cost?
You may check Januvia prices from this page.