Generic Name: fluticasone furoate and vilanterol
Drug Class: corticosteroid and long-acting beta 2-adrenergic agonist
Breo Ellipta is an oral prescription inhalation used as a long-term maintenance treatment of airflow obstruction. It is prescribed to reduce exacerbations among patients with chronic obstructive pulmonary disease or COPD, with chronic bronchitis and emphysema.
This is available in Breo Ellipta 100/25 mcg and Breo Ellipta 200 25 mcg inhalation powder.
Breo Ellipta Mechanism of Action
This inhalation has two actions. First, it acts on multiple cell types and mediators that are responsible for inflammation. It works directly in the lungs by reducing the swelling of the airways to make breathing easier. In addition, it stimulates the adenyl cyclase enzyme, which converts adenosine triphosphate into cyclic adenosine monophosphate. Increased levels of cyclic AMP can result in bronchial smooth muscle relaxation and inhibition of the release of immediate hypersensitivity mediators.
How to Use Breo Ellipta
Before you take this prescription product, you must read the drug information leaflet or brochure that comes with it. Do not use this oral inhaler unless you thoroughly understand all the information and instructions. You should consult your doctor or pharmacist for more information.
This is usually prescribed once a day. Remember to use the inhaler at the same time each day. Establish a dosing schedule so you don’t miss any doses. Do not increase/decrease your Breo Ellipta dosage or use this inhaler more frequently than prescribed. Avoid using this product more than once each day. Do not use this product if you are using a quick-relief inhaler.
Step-by-step Guide on using Breo Ellipta:
- Open the inhalation device by sliding the cover down until you see the mouthpiece. Check the counter if it counts down by 1 number, as this signifies that your inhaler is ready to use. Be careful not to shake the inhaler.
- Hold the device away from your face.
- Exhale fully and deeply.
- Put your mouth on the mouthpiece and seal your lips firmly on it. Inhale slowly and deeply through the mouth. Your fingers must not block the air vent.
- Remove the mouthpiece and hold your breath for around 4 secs or as long as it is comfortable for you.
- Exhale slowly. It is normal to be able to taste or feel the powder in your mouth.
- Clean the mouthpiece with dry tissue and close the device by sliding the cover upward.
- Rinse your mouth right after.
Breo Ellipta Side Effects
Mild & Common Side Effects:
-Back or joint pain
Severe Side Effects:
-White patches inside the mouth
-Unusual weight gain
-Poor wound healing
-Easy bruising or bleeding
-Persistent sore throat
Note that this is not a full/complete list of the side effects of Breo Ellipta.
Contact your doctor or other health care professional if you experience severe or persistent adverse reactions.
Warnings and Precautions
Do not use Breo Ellipta if you have a known allergy to fluticasone, vilanterol, milk proteins, or any inactive ingredients it may contain. Keep an eye out for signs of allergic reactions, such as difficulty breathing, swelling of the face and neck, severe dizziness, swollen lymph nodes, and hives/itchiness. If this happens, stop using the oral inhalation and seek immediate medical attention.
Breo Ellipta may be contraindicated for people with a history of any recent infection, heart problem, eye problem, osteoporosis, hyperthyroidism, liver problem, high blood pressure, diabetes, seizure disorder, and depression. Additionally, because of possible interactions between drugs, it is important to discuss all prescription and non-prescription medications, supplements, and herbal products you are taking.
Breo Ellipta can cause QT prolongation, which could be considered a medical emergency. Symptoms are severe dizziness and fainting. You may prevent this by staying hydrated and avoiding water pills. You should also be monitored for low levels of potassium and magnesium in the blood, as they may also lead to QT prolongation.
A weakened defense system can be caused by the use of steroids. This drug can possibly mask signs of infection or make you more likely to get an infection. Do not come in contact with people who have or have recently acquired infections, such as flu, chickenpox, or measles.
If you are pregnant/breastfeeding, you should talk to your doctor about the possible risks of this product and the possible effects on unborn babies and breastfed infants.
Frequently Asked Questions (FAQs)
What does Breo Ellipta do for you?
This inhaler is used to reduce breathing symptoms, such as wheezing, coughing, and shortness of breath. This is usually prescribed to patients with COPD.
Is Breo Ellipta a steroid?
This product has an inhaled corticosteroid component. It also contains a long-acting beta2-adrenergic agonist or LABA.
Should I take Breo Ellipta in the morning or at night?
There is no specific time to take this inhaler. You may use it any time of the day, provided that you follow a dosing schedule.
Can Breo Ellipta cause weight gain?
Yes, it is possible to gain weight while using this oral inhaler. This is due to the high cortisol levels that are among the rare adverse reactions to this drug.
Can Breo Ellipta raise BP?
This inhalation can possibly affect your blood pressure. Some patients report an increase in blood pressure while on this medication.
Can you buy Breo Ellipta over the counter?
You cannot purchase this oral inhalation over the counter. A prescription is required to purchase this product.
How much does Breo Ellipta cost?
Click here to check the list of our Breo Ellipta prices on this page. Get the best deals when you order from Pharma passport.