Generic Name: esomeprazole magnesium
Drug Class: proton pump inhibitors (PPI)
What is Nexium?
Nexium is an oral prescription drug used to treat gastroesophageal reflux disease (GERD). It also reduces the risk of NSAID-associated gastric ulcer and duodenal ulcer recurrence by H. pylori eradication. It is also used for pathological hypersecretory conditions, like Zollinger-Ellison syndrome.
This is available in Nexium 40mg and 20mg delayed-release tablets.
Nexium Mechanism of Action
This PPI suppresses gastric acid secretion by inhibiting hydrogen potassium ATPase in the gastric parietal cell. It blocks the final step in acid production, therefore decreasing gastric acidity.
How to Take Nexium
It is necessary to read the product information leaflet or medication guide before taking Nexium. You must not take any medication unless you have understood the uses and directions. Ask your doctor or pharmacist for further medical advice or additional details.
The tablet should only be taken by mouth. This is usually prescribed once daily on an empty stomach. It is best to take it one hour before your meal. Take the tablet and drink fluids immediately afterward. Chewing or crushing this drug is not recommended.
Make a dosing schedule. If you are also prescribed sucralfate, take it at least 30 minutes after taking esomeprazole. Do not increase or decrease your Nexium dosage. You should not also take this oral drug more frequently than advised.
Nexium Side Effects
Mild & Common Side Effects:
Severe Side Effects:
-Low magnesium level in the blood
-Signs of lupus
-Symptoms of C. difficile infection (fever, persistent diarrhea, abdominal pain, blood or mucus in the stool)
-Vitamin B12 deficiency
Note that this is not a full/complete list of the side effects of Nexium.
If you experience severe or persistent adverse reactions, discontinue medication and call your doctor or any health care professional.
Warnings and Precautions
Do not take this prescription drug if you have a known allergy to esomeprazole, lansoprazole, omeprazole, or any Nexium ingredients. Always be watchful for any signs of serious allergic reactions, including trouble breathing, swelling of the face and neck, severe dizziness, swollen lymph nodes, hives/itchiness, and skin rashes. When this occurs, stop taking the oral medication and seek emergency medical help immediately.
Nexium may be contraindicated for people with a history of electrolyte imbalances, vitamin deficiency, kidney problems, liver disease, and lupus. Also, due to possible drug interactions, you should discuss all the prescription medications, nonprescription medications, supplements, and herbal products you are taking.
Taking esomeprazole can increase the risk of bone fractures, especially if used in higher doses and for a long period of time. Your doctor may recommend taking calcium and vitamin D supplements. You can also do weight-bearing exercises to prevent bone loss.
It is preferable for pregnant moms to avoid this drug as it is still not entirely known if this drug can cause harm to unborn babies. For breastfeeding moms, it is also unknown if this drug can pass into the breastmilk. Talk to your doctor regarding all the possible risks.
Frequently Asked Questions (FAQs)
1. What does Nexium do?
This proton pump inhibitor works by decreasing the production of gastric acid. It relieves symptoms caused by GERD, erosive esophagitis, and other GI problems, such as heartburn, persistent cough, and difficulty swallowing.
2. When should I take Nexium?
You must take this medication at least 30 minutes prior to your meal. Do not chew this delayed-release tablet.
3. How long will it take for Nexium to work?
It can take around 1 to 4 days before this oral drug improves your condition. Note that this oral medication does not provide immediate relief.
4. Which is better, Prilosec or Nexium?
Nexium vs Prilosec – Both products are proven effective in treating GERD and other gastrointestinal conditions. However, esomeprazole is known to work more effectively and faster compared to Prilosec.
5. Why can’t you take Nexium for more than 14 days?
Long-term use of PPI is associated with acute kidney injury and chronic kidney disease. Do not take this prescription drug longer than prescribed.
6. Can you purchase Nexium over-the-counter?
This proton pump inhibitor is available by prescription. You will have to present a valid prescription from your physician before getting this medication.
7. How much does Nexium cost?
You may check the pricing of this product by clicking here. Get the best deals when you order from Pharma Passport.