What is Trelegy Ellipta?
Trelegy Ellipta (generic name: fluticasone, umeclidinium, & vilanterol) is a respiratory prescription inhalation that is indicated as maintenance treatment for people with asthma and chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. It helps in controlling and preventing breathing symptoms, such as shortness of breath, coughing, and wheezing.
Trelegy Ellipta is a combination of an inhaled corticosteroid, an anticholinergic, and a long-acting beta2-adrenergic agonist (LABA).
This is available in Trelegy Ellipta 100/62.5/25 mcg and 200/62.5/25 mcg in 30 inhalations.
How does Trelegy Ellipta work?
Since Trelegy Ellipta is a combination of three different types of medication, it also has other actions. It has a wide range of actions on multiple cell types and mediators, which decrease inflammation. It also inhibits the m3 receptor at the smooth muscle, which results in bronchodilation. Lastly, it also increases cyclic adenosine monophosphate (AMP), which contributes to relaxing the bronchial smooth muscle and impedes the release of mediators of immediate hypersensitivity from cells.
How should I use Trelegy Ellipta?
You must read the patient information guide and use this inhaler exactly as prescribed by the doctor. Administer your dose once daily. Do not increase or decrease your Trelegy Ellipta dose, and do not use this more frequently than intended.
Step by step Medication Guide:
- Remove the back lid of the packaging. Throw the desiccant that comes with it properly. Look for the counter that shows the number of doses in the inhalation device. It should display “30”.
- Slide the cover of the device down. The mouthpiece will show, and you will hear a click. The number displayed on the counter will count down by 1, which means that the device is ready to use.
- Exhale deeply and fully.
- Put the mouthpiece inside your mouth and seal your lips around it. Ensure that your hands and fingers are not blocking the air vent.
- Inhale deeply and slowly from the mouthpiece.
- Hold your breath for around 4 seconds and remove the inhalation device away from your mouth.
- Exhale slowly and close the inhaler by sliding the cover back up.
- Rinse your mouth using tap water and spit it out.
Trelegy Ellipta side effects
The common side effects of this oral inhalation are sore throat, hoarseness, cough, changes in taste, and headache. Additionally, the severe adverse effects that you have to report are white patches in the mouth, any signs of infection, increased thirst, bone pain, tremors, muscle weakness, painful urination, elevated blood pressure, severe wheezing, chest pain, irregular heartbeat, severe dizziness, vision changes, any mental or mood problems. Call your doctor if any severe adverse reaction occurs.
Precautions / Contraindications
Trelegy Elliipta may increase the risk of QT prolongation. Do not take any form of diuretics and drink plenty of fluids to avoid this. You should also be watchful for low potassium or magnesium levels in the blood, as these conditions can further increase the risk of QT prolongation. Consider it a medical emergency once you experience increased heart rate, irregular heartbeat, severe dizziness, and fainting.
This inhaled corticosteroid may make you more prone to infection and/or develop severe symptoms of infection. Avoid getting in contact with patients who have an infection and observe good personal hygiene at all times.
Trelegy Ellipta inhaler should not be used if you have a known allergy to fluticasone, umeclidinium, vilanterol, milk proteins, or other inactive ingredients Trelegy Ellipta may contain. Signs of severe allergic reactions are swelling of the face and neck, swollen lymph nodes, skin rashes, itchiness, trouble breathing, and severe dizziness. If this happens, get emergency medical help.
This oral inhalation is also contraindicated among people with a history of certain medical conditions, such as recent or current infection, heart problems, osteoporosis, eye problems, enlarged prostate, hyperthyroidism, diabetes, liver disease, and seizures. Due to potential drug interactions, you must also talk about all supplements, herbal products, prescription medications, and nonprescription medications you are taking.
Frequently Asked Questions
1. Is it necessary to rinse my mouth after taking Trelegy Ellipta?
Rinsing the mouth is essential after administering the Trelegy Ellipta inhaler in order to avoid oral thrush.
2. How much does Trelegy Ellipta cost?
You may check for Trelegy Ellipta price from this page.
3. Is Trelegy Ellipta safe for pregnant and breastfeeding women?
It is best to discuss the possible risks and benefits with your physician, as it is unknown if this oral inhalation can cause harm to pregnant and breastfeeding moms and their babies.
4. Can children use Trelegy Ellipta?
This inhaler should not be prescribed for children or adolescents under the age of 18.