Generic Name: linaclotide
Drug Class: guanylate cyclase-C agonist
Linzess (linaclotide) is an oral prescription drug prescribed to adults with irritable bowel syndrome with constipation and chronic idiopathic constipation. It improves the texture of the stool and relieves symptoms, such as bloating, abdominal discomfort, straining, and feeling of incomplete bowel movements or emptying.
This is available in Linzess 145 mcg, 290 mcg, and 72 mcg capsules.
Mechanism of Action
This drug increases both the extracellular and intracellular cyclic guanosine monophosphate (cGMP) levels. It accelerates gastrointestinal transit and also relieves intestinal or abdominal pain.
How to Take Linzess
Before taking this medication, it is necessary to read the information leaflet or medication guide given by a healthcare professional. You must not take any medication unless you have understood the uses and directions. Ask your doctor or pharmacist for further medical advice or additional details.
This capsule is only meant to be taken by mouth. This is usually prescribed once a day, on an empty stomach. Take it thirty minutes prior to breakfast or your first meal of the day. Swallow the capsule whole and drink fluids right after.
Make a dosing schedule. Do not increase or decrease your Linzess dosage. You should not also take this oral drug more frequently than advised.
Linzess Side Effects
Mild & Common Side Effects:
Severe Side Effects:
-Severe abdominal pain
Note that this is not a full/complete list of the side effects of Linzess.
If you experience severe or persistent adverse reactions, discontinue medication and call your doctor or any health care professional.
Warnings and Precautions
Do not take this prescription drug if you have a known allergy to linaclotide or any inactive ingredients the capsule may contain. Always be watchful for any signs of serious allergic reactions, including trouble breathing, swelling of the face and neck, severe dizziness, swollen lymph nodes, hives/itchiness, and skin rashes. If this occurs, stop taking this oral medication and seek emergency medical help immediately.
This medication may be contraindicated for people with a history of any stomach or intestinal blockage. Also, due to possible drug interactions, you should discuss all the prescription medications, nonprescription medications, supplements, and herbal products you are taking.
If you are pregnant/breastfeeding, you should talk to your doctor about the possible risks of this product and the possible effects on unborn babies and breastfed infants.
Frequently Asked Questions (FAQs)
1. What does Linzess do?
Physicians prescribe Linzess for constipation, usually caused by irritable bowel syndrome. Note that this medication is not a laxative.
2. How long does Linzess take to kick in?
Usually, this oral drug starts to relieve symptoms within a week. It can lessen symptoms like constipation, bloating, and abdominal pain.
3. Can you drink alcohol with Linzess?
Drinking alcohol may worsen IBS, and it can also trigger the adverse effects of this medication. With this, you must restrict your alcohol consumption while using this drug.
4. Does Linzess cause weight loss?
Although there is no direct link between Linzess & weight loss, some people taking this medication for constipation do experience losing weight.
5. Who should not take Linzess?
Children below 6 years of age should not take this medication because of the risk of dehydration. This is also contraindicated for people with gastrointestinal blockage.
6. How much does Linzess cost?
You may check the pricing of this product by clicking here. Get the best deals when you purchase from Pharma Passport.
7. Is Linzess over the counter?
This product is a prescription medication. You cannot purchase this drug from any pharmacy without a valid prescription.