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Trulance 
Description
Generic Name: plecanatide
Drug Class: guanylate cyclase-C agonist
Trulance Indications
Trulance is an oral prescription drug used to treat irritable bowel syndrome with constipation and chronic idiopathic constipation. By improving stool consistency, it relieves bloating, abdominal discomfort, straining, and a feeling of incomplete bowel movements or emptying of the bowels.
Trulance Dosage Forms
This is available in Trulance 3 mg tablets.
Trulance Mechanism of Action
There is an increase in both intracellular and extracellular cyclic guanosine monophosphate (cGMP) levels as a result of this drug. As well as accelerating gastrointestinal transit, it alleviates abdominal and intestinal pain.
How to Take Trulance
Before taking Trulance, it is necessary to read the information leaflet or medication guide given by a healthcare professional. It is important that you fully understand the uses and directions of any medication before you take it. If you need additional medical advice or information, consult your doctor or pharmacist.
Trulance is usually prescribed once a day and is only meant to be taken by mouth with or without a meal. If you need to cut or crush the tablet, ask for supervision from a medical provider.
Establish a dosing schedule. Do not increase or decrease your Trulance dosage. You should also not take this oral drug more frequently than advised.
Trulance Side Effects
Mild & Common Side Effects:
-Diarrhea
-Abdominal discomfort
-Flatulence
-Bloating
Severe Side Effects:
-Severe diarrhea
-Persistent abdominal pain
-Dehydration
Note that this is not a full/complete list of the side effects of Trulance medication.
If you experience severe or persistent adverse reactions, stop taking this drug and immediately inform your doctor or health care professional.
Warnings and Precautions
Do not take this prescription drug if you have a known allergy to plecanatide or any inactive ingredients the tablet may contain. Observe any signs of serious allergic reactions, including swelling of the face and neck, hives and skin rashes, breathing difficulties, and swollen lymph nodes. It is important to discontinue use of this medication if this occurs and to seek emergency medical attention right away.
This medication may be contraindicated for people with a history of any stomach or intestinal blockage. Also, make sure to discuss with your doctor all medications, supplements, and herbal products you are taking for possible drug interactions.
Pregnant or breastfeeding women should consult their doctor about the possible risks of this product and its possible effects on their unborn babies.
How much does Trulance cost in Canada?
Plecanatide tablets for IBS with constipation in adults are available from our online pharmacy. Check the top of this page to see your options.
Frequently Asked Questions (FAQs)
What is Trulance used for?
Trulance (plecanatide) is a prescription tablet classified as a guanylate cyclase-C agonist. It is used to relieve chronic idiopathic constipation (CIC) and irritable bowel syndrome or IBS with constipation. This is not prescribed for children younger than 6 years old.
How long after taking Trulance do you have a bowel movement?
It may take a week for this oral medication to work. People who are taking this drug report mild diarrhea within the first four weeks of taking this drug.
What is the best time of the day to take Trulance?
You may take this prescription tablet any time of the day, but it is best to take this medication at the same time each day. There is no recommended time for administering plecanatide.
How is Trulance different from Linzess?
Trulance vs Linzess – These medications are both used to manage constipation. However, Trulance is a newer medication that can be taken with or without food.
Is Trulance a stool softener?
This oral drug is not a laxative or stool softener. Stool softeners only provide instant relief and are only being administered as needed.