Generic Name: entacapone
Drug Class: COMT inhibitors
Comtan is an oral prescription drug used to treat end-of-dose “wearing-off” among patients with Parkinson’s disease. This is usually given together with other medications, such as levodopa and carbidopa. Its effectiveness has not been established among people with Parkinson’s disease who do not experience end-of-dose “wearing-off”.
Comtan Dosage Forms
This is available in Comtan 200 mg tablets.
Comtan Mechanism of Action
This drug works by inhibiting catechol-O-methyltransferase or COMT while inhibiting the plasma pharmacokinetics of levodopa. When administered with carbidopa and levodopa, it stops the breakdown of the dopamine precursor and can help with its metabolism. This prevents the return or worsening of Parkinson’s symptoms.
How to Take Comtan
Before starting to take this Comtan, it is necessary to read the information leaflet or medication guide given by a healthcare professional. Before taking a medication, make sure you understand its purpose and directions. For further medical advice or additional details, contact your doctor or pharmacist.
This tablet is only meant to be taken by mouth and is usually prescribed up to 8 times a day together with each dose of levodopa or carbidopa. Take Comtan with or without a meal. Swallow the oral tablet and drink fluids right after.
Make a dosing schedule. Do not increase or decrease your Comtan dosage as it depends on the liver function, overall medical condition, and response to therapy. It is also important not to exceed the suggested dosage of this oral drug. Further, never stop taking it abruptly because doing so may result in worsening of Parkinson’s symptoms.
Comtan Side Effects
Mild & Common Side Effects:
- Dry mouth
- Abdominal pain
- Increased sweating
- Uncontrolled movements
- Brownish-orange urine
Severe Side Effects:
- Suddenly falling asleep
- Mental or mood changes
- Unusual strong urges
- Easy bruising and bleeding
- Muscle stiffness
- Sore or painful muscles
- Muscle weakness
- Severe diarrhea
- Pain with breathing
- Trouble breathing
Note that this is not a full/complete list of the side effects of Comtan.
In the event of severe or persistent side effects, stop taking your medication and contact your doctor or healthcare professional.
Comtan Warnings and Precautions
Do not take this prescription drug if you have a known allergy to entacapone or any Comtan ingredients each film-coated tablet may contain. Observe any signs of serious allergic reactions, including breathing difficulties, swelling of the face and neck, dizziness, swollen lymph nodes, hives, and skin rashes. It is important to discontinue use of this medication if this occurs and to seek emergency medical attention right away.
This medication may be contraindicated for people with a history of alcohol abuse, depression, schizophrenia, any mental or mood conditions, sleep problems, low blood pressure, and liver problems. Additionally, due to possible drug interactions, you should discuss all the prescription medications, nonprescription medications, supplements, and herbal products you are taking.
Dizziness, lightheadedness, and drowsiness are among the common adverse effects of this medication. When performing tasks that require alertness and clear vision, exercise safety precautions. In addition, you should limit your consumption of alcoholic beverages.
This type of drug may cause hallucinations and other psychotic-like behavior. Some patients develop new or worsening mental status or behavioral changes while on this treatment or after taking this medication. Once you notice any changes in behavior, you must notify your physician immediately.
This oral medication can also make you more sensitive to sun exposure and increase the risk of skin cancer. While using this drug, limit your exposure to the sun and avoid indoor tanning. Always wear protective clothing and apply sunblock lotion when going out.
If you are pregnant or breastfeeding, this oral medication must only be taken if absolutely necessary. It is unknown if it can cause harm to unborn babies and breastfed infants. It is necessary to discuss all the possible risks with a healthcare provider.
How much does Comtan cost in Canada?
The Comtan price in Canada is always a lot cheaper than in the United States. You may purchase this oral drug from our website, or you may also order your prescriptions by phone.
Get the best Comtan price when you order your prescription drugs from PharmaPassport.
Frequently Asked Questions (FAQs)
What is Comtan used for?
Comtan (entacapone) is being prescribed to patients with Parkinson’s disease. This is often given with carbidopa or levodopa. This is only prescribed to patients who have experienced “wearing off” symptoms.
What happens when you stop taking Comtan?
Once you stop taking this oral drug suddenly, you can possibly experience worsening symptoms of Parkinson’s disease, and it can also pose other dangerous effects. This is why you should not stop taking this drug unless advised by a medical professional.
Does Comtan affect blood pressure?
Yes, entacapone can increase the risk of low blood pressure or hypotension. It can also cause a sudden drop in blood pressure when you stand from a lying down or sitting position. It is necessary to monitor your blood pressure while taking this product.
When is the best time to take Comtan?
You must take this tablet based on a dosing schedule. It may be taken with food or on an empty stomach. There is no recommended time to take this medication. You may also ask your physician or pharmacist.
Is there an alternative to Comtan?
At present, there are no available generic or brand name alternatives to this oral medication. If this product is not working for you, you must talk to your doctor so that you will be prescribed with other treatment options.
Can you get Comtan over the counter?
This oral product is a prescription drug. This product must be purchased from a pharmacy with a valid prescription. Do not use this medication unless prescribed.
Can I buy Comtan online?
Comtan is available for purchase at your local pharmacy and any online pharmacies. But ordering this from our online store does not only provide you a hassle-free transaction but also affordable prices.