Generic Name: rosuvastatin calcium
Drug Class: HMG Co-A reductase inhibitor
Crestor is an oral prescription drug used to reduce total cholesterol, apolipoprotein B, triglyceride levels, and low-density lipoprotein cholesterol while increasing high-density cholesterol among people with primary hyperlipidemia and mixed dyslipidemia.
It is also used for people with hypertriglyceridemia, primary dysbetalipoproteinemia, and homozygous familial hypercholesterolemia. Additionally, this is used to slow atherosclerosis progression and reduce the risk of stroke, myocardial infarction, and arterial revascularization procedures among those with multiple risk factors.
This is available in Crestor 20 mg, 10 mg, 5 mg, and 40 mg tablets.
Crestor Mechanism of Action
It catalyzes HMG-CoA conversion to mevalonate, which is a step in cholesterol biosynthesis. This works directly on the liver by decreasing the concentrations of hepatic cholesterol in order to upregulate the hepatic low-density lipoprotein receptors and increase the hepatic uptake of LDL. It also reduces other lipid levels while increasing the high-density lipoprotein cholesterol.
How to Take Crestor
Before taking Crestor, it is necessary to read the drug information leaflet or medication guide given by a healthcare professional. Do not take Crestor or any medicine unless you have understood the uses and directions or you’ve talked to your doctor or pharmacist.
Crestor is only meant to be taken by mouth. This is usually prescribed once a day and preferably at the same time each day. It can be consumed with or without food. Swallow the tablet and drink fluids right after.
Make a dosing schedule. If you are prescribed an antacid that either contains magnesium or aluminum, take it two hours after taking this medication. Do not increase or decrease your Crestor dosage. You should also not take this oral drug more frequently than advised.
This oral medication is only an adjunct to proper diet and regular exercise. It may not work as well if lifestyle changes are not applied. Always eat a healthy balanced meal and do exercise regularly.
Crestor Side Effects
Mild & Common Side Effects:
Severe Side Effects:
-Mild memory problems
-Rhabdomyolysis and autoimmune myopathy
-Muscle pain or weakness
-Changes in urine output
-Severe abdominal pain
-Yellowish eyes and skin
Note that this is not a full/complete list of the Crestor side effects in women and men.
If you experience severe or persistent adverse reactions, discontinue medication and talk to your doctor or healthcare professional.
Warnings and Precautions
Do not take this prescription drug if you have a known allergy to rosuvastatin or any inactive ingredients the tablet may contain. Always watch for signs of serious allergic reactions, including trouble breathing, swelling of the face and neck, severe dizziness, swollen lymph nodes, hives/itchiness, and skin rashes. If this occurs, stop taking Crestor and seek emergency medical help immediately.
This medication may be contraindicated for people with a history of alcohol abuse, kidney disease, and liver disease. You should discuss all the prescription medications, nonprescription medications, supplements, and herbal products you are taking with your doctor due to possible drug interactions.
Avoid or restrict your alcohol consumption while on this statin therapy. Drinking alcohol can further increase the risk of liver damage, especially if combined with rosuvastatin.
Crestor and grapefruit may interact and cause adverse reactions. This is because grapefruit contains compounds that can negatively affect statins. Do not eat grapefruit and drink grapefruit juice while you are on this therapy.
Pregnant moms must avoid this statin because it is known to cause harm to unborn babies. For breastfeeding moms, this medication can pass into breastmilk, so you must take this oral drug only if extremely necessary. It is important to discuss with a healthcare provider all possible risks.
Frequently Asked Questions (FAQs)
What is Crestor used for?
Crestor (rosuvastatin) is primarily used to lower bad cholesterol while increasing the level of good cholesterol. This is given as an adjunct to proper diet and exercise.
Is Crestor a statin?
Yes, this product is a statin medication. Statins are referred to as HMG-CoA reductase inhibitors, which are lipid-lowering drugs.
What is the best time to take Crestor?
This statin could be administered any time of the day. Just remember to take it based on a dosing schedule.
Is Crestor a stronger statin than Lipitor?
Crestor vs Lipitor – These drugs belong to the same drug class. However, Crestor is known to be more potent compared to Lipitor (atorvastatin).
Does Crestor make you gain weight?
There is no direct link between rosuvastatin and weight gain. Any changes in weight are not among the direct side effects of Lipitor.
Can I buy Crestor over the counter?
This product is a prescription drug. You need to have a valid prescription before purchasing from any pharmacy.
How much does a 30-day delivery of Crestor cost?
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