Generic Name: deferasirox
Drug Class: iron-chelating agent
Exjade is an oral prescription suspension used to treat chronic iron overload due to blood transfusions. It is also used among patients with non-transfusion-dependent thalassemia syndrome and has a liver iron concentration of <5 mg iron per gram of dry weight & serum ferritin greater than 5 mg Fe/g dw.
Exjade Dosage Forms
This is available in Exjade 500 mg, 125 mg, and 250 mg tablets.
Exjade Mechanism of Action
It works on iron toxicity by binding trivalent iron, which forms a stable complex. This allows the excretion of this compound through the urine. It is known to bind iron with high affinity but has a very low affinity to zinc and copper.
How to Take Exjade
Before taking this medication, it is necessary to read the drug information leaflet or medication guide given by a healthcare professional. It is important to understand the uses and directions of drugs before using them. Get medical advice or additional details from your doctor or pharmacist.
This oral solution should only be taken by mouth. This is usually prescribed once a day, on an empty stomach. Take it at least 30 minutes prior to eating. To prepare the solution, stir the tablet into a glass of water, apple juice, or orange juice until it has completely broken apart and dissolved into the liquid. Drink this solution immediately after preparation. Then, add more liquid into the glass and stir the remaining drug. Drink the rinsing liquid right away.
Make a dosing schedule. Do not increase or decrease your Exjade dosage.
Exjade Side Effects
Mild & Common Side Effects:
-Loss of appetite
Severe Side Effects:
-Persistent sore throat
-Easy bruising or bleeding
Note that this is not a full/complete list of the side effects of Exjade.
If you experience severe or persistent adverse reactions, discontinue medication and talk to your doctor or health care professional.
Warnings and Precautions when using Exjade
Do not take this prescription drug if you have a known allergy to deferasirox or any inactive ingredients the solution may contain. Be aware of any serious allergy symptoms, including trouble breathing, swelling of the face and neck, severe dizziness, swollen lymph nodes, hives, and rashes. This means that you should immediately discontinue using this medication and seek emergency medical help.
This medication may be contraindicated for people with a history of advanced cancer, low platelet count, myelodysplastic syndrome, liver disease, and kidney disease. This oral drug can also increase the risk of the aforementioned conditions. Additionally, you should discuss all prescription drugs, nonprescription drugs, supplements, and herbal products you are taking due to possible drug interactions.
Dizziness and blurred vision are among the common adverse reactions to this medication. Practice safety caution when doing tasks that would need alertness and clear vision, especially driving. You must also limit drinking alcohol while taking this capsule.
Pregnant and breastfeeding women must not take this oral medication unless absolutely necessary. This solution can pass into the breastmilk and may affect nursing infants.
How much does Exjade cost?
To check for Exjade price, you may refer to the list posted on this page.
Frequently Asked Questions (FAQs)
What is Exjade used for?
Exjade (deferasirox) is prescribed to manage ongoing transfusional iron overload. It is also used for people with certain blood disorders. Physicians prescribe Exjade sickle cell for anemia patients.
When should I take Exjade?
This type of drug should be given 30 minutes before your meal. You may take it any time of the day, provided that you follow a dosing schedule.
What is the difference between Exjade and Jadenu?
Exjade vs Jadenu – These medications contain the same active ingredient. However, while Exjade is only available as a dispersible tablet that is taken on an empty stomach, Jadenu is available in oral tablet form that can be taken with or without a light meal.
How long does it take Exjade to work?
This drug may take one to two hours to start working. You have to take it regularly to see the full effects of this medication.
When should I stop taking Exjade?
You should continue taking this oral suspension until the doctor prescribes it. Your length of treatment will be based on the evaluation made by your physician.
Do I need a prescription for Exjade?
This product is a prescription medication. You will need to get a valid prescription from your doctor to purchase this medication.