Generic Name: empagliflozin and metformin hydrochloride
Drug Class: sodium-glucose co-transporter 2 (SGLT2) inhibitor and biguanide
Synjardy is an oral prescription drug used to improve glycemic control among adults with type 2 diabetes mellitus when treatment with empagliflozin and metformin is necessary. This is prescribed together with proper diet and exercise. This oral medication is not indicated for type 1 diabetes and diabetic ketoacidosis.
Synjardy Dosage Forms
This is available in Synjardy 12.5 mg 1000 mg, 12.5 mg/500 mg, 5 mg/1000 mg, and 5 mg/500 mg tablets.
Synjardy Mechanism of Action
This is a combination product of an SGLT2 inhibitor and a biguanide.
First, it reduces the reabsorption of filtered glucose from the tubular lumen and lessens the renal threshold of glucose, resulting in an increase in urinary glucose excretion.
Second, it improves glycemic control by decreasing the production of hepatic glucose, decreasing the absorption of glucose in the intestines, and improving insulin sensitivity through increasing peripheral glucose uptake and utilization.
How to Take Synjardy
Before starting with this treatment, it is necessary to read the information leaflet or medication guide given by a healthcare professional. It is important that you have a complete understanding of the uses and directions of the medication before taking it. A pharmacist or doctor should be consulted if you need further medical advice.
Synjardy tablet is only meant to be taken by mouth and is usually prescribed two times a day. You must take it with a meal and make sure to drink plenty of fluids. Cutting or crushing this product is not recommended.
Make a dosing schedule. Do not increase or decrease your Synjardy dosing. It is also advisable not to take this oral drug more frequently than prescribed.
Synjardy is only an adjunct to proper diet and regular exercise and may not work well if there are no lifestyle changes. Do regular exercise and always eat a healthy balanced meal.
Synjardy Side Effects
Mild & Common Side Effects:
Severe Side Effects:
-Changes in urine output
-Low blood sugar
-High blood sugar
Note that this is not a full/complete list of the side effects of Synjardy.
In the event of severe or persistent side effects, stop taking your medication and contact your doctor or healthcare professional.
Warnings and Precautions when using Synjardy
Do not take this prescription drug if you have a known allergy to empagliflozin, metformin, or any inactive ingredients the tablet may contain. Observe any signs of serious allergic reactions, including breathing difficulties, swelling of the face and neck, dizziness, swollen lymph nodes, hives, and skin rashes. When this happens, stop using the medication as soon as possible and seek emergency medical help.
This medication may be contraindicated for people with a history of severe asthma, COPD, liver disease, kidney disease, heart disease, yeast infections, dehydration, vitamin B12 deficiency, anemia, and alcohol abuse. It is also important to discuss all prescription medications, nonprescription medications, supplements, and herbal products you are taking since there may be drug interactions.
Dizziness, drowsiness, and blurred vision are commonly experienced when the blood sugar is too high or too low. Keeping alert and clear vision is essential when performing tasks requiring alertness.
Restrict your intake of alcoholic beverages. Alcohol can trigger certain adverse effects. It can also increase the risk of low blood sugar and lactic acidosis. Diuretics and dehydration can also contribute to lactic acidosis, so avoid them if possible.
Metformin can cause menstrual changes and promote ovulation. Thus, increasing the chance of getting pregnant. Consult your healthcare provider for reliable and safe birth control methods.
Pregnant women and breastfeeding mothers must only use this drug in extreme circumstances. Getting a health provider’s advice on all the risks involved is essential. Furthermore, pregnancy can either cause or worsen diabetes.
How much does Synjardy cost in Canada?
Get the best deals when ordering from PharmaPassport.com. Check the top of this page for prices.
Frequently Asked Questions (FAQs)
What is Synjardy used for?
Synjardy is used to control high blood sugar levels caused by type 2 diabetes mellitus. It helps prevent complications like kidney damage, nerve problems, sexual dysfunction, and blindness.
Does Synjardy cause weight loss?
Yes, there is a link between Synjardy & weight loss. Patients who are taking this medication report modest weight loss after weeks or months of taking this medication.
What is the best time to take Synjardy?
This type of anti-diabetes medication is usually prescribed twice daily, usually with breakfast and dinner. It is best to take this oral tablet with a dosing schedule.
What are some Synjardy alternatives?
Among the alternatives of this medication are Xigduo, Segluromet, and Invokamet. These are all combination drugs that contain an SGLT2 inhibitor and a biguanide.
Is Synjardy better than metformin?
This combination medication also contains metformin. It means that it works in more ways compared to metformin.
Is Synjardy over the counter?
This product is a prescription medication for diabetes. When purchasing this product from any pharmacy, you must present a valid prescription.