Generic Name: vortioxetine
Drug Class: selective serotonin reuptake inhibitor or SSRI
Trintellix (vortioxetine) is an oral prescription indicated to treat adults with major depressive disorder or MDD. This type of depression is characterized by a persistent feeling of sadness and a loss of interest in daily activities. This drug helps enhance one’s mood, energy level, appetite, and sleep.
This is available in Trintellix 20 mg, 15 mg, 10 mg, and 5 mg immediate-release tablets.
Trintellix Mechanism of Action
The mechanism of action of this oral antidepressant is still not fully understood. However, it is thought to enhance the serotonergic activity in the central nervous system (CNS) by inhibiting the reuptake of serotonin. It also acts as a serotonin receptor modulator. As a result, it restores the balance of natural substances or neurotransmitters in the brain.
How to Use Trintellix
Before taking Trintellix, it is necessary to read the information leaflet or medication guide given by a healthcare professional. You must not take any medication unless you have understood all the information regarding it. Ask your doctor or pharmacist for further medical advice or additional details.
This tablet is only meant to be taken by mouth. You may administer your dose with or without a meal. Swallow the tablet entirely and drink fluids right after. Avoid splitting, chewing, or crushing the immediate-release tablet.
Keep a dose schedule to prevent missing doses. This is usually prescribed once daily. For a missed dose, take it right away, except if it is almost time for your next scheduled dose. Do not increase or decrease your Trintellix dosage as it is based on your medical condition, other drugs you are taking, & response to treatment. You should also keep taking this drug and do not stop taking it abruptly. Doing so can lead to withdrawal symptoms. You may experience headaches, runny nose, mood swings, and muscle stiffness.
Trintellix Side Effects
Mild & Common Side Effects:
-Decreased sexual interest
Severe Side Effects:
-Shaking or tremor
-Numbness or tingling
-Inability to keep still
-Easy bruising and bleeding
-Symptoms of serotonin syndrome (hallucinations, fast heartbeat, unusual agitation, unexplained fever, muscle twitching, severe dizziness, persistent nausea, and vomiting)
Note that this is not a full/complete list of the side effects of Trintellix.
If you experience severe or persistent adverse reactions, discontinue taking Trintellix and consult your doctor or any healthcare professional.
Precautions / Warnings
Do not take this oral prescription if you have a known allergy to vortioxetine or any inactive ingredients each oral tablet may contain. Be cautious for signs of a severe allergic reaction, including difficulty breathing, swelling of the face and neck, severe dizziness, hives/itchiness, and skin rashes. If this happens, discontinue this antidepressant immediately, and alert your local medical emergency line.
Certain diseases or disorders may significantly affect how you will respond to this treatment. Disclose full medical history to your doctor, including any history of bipolar disorder, suicide attempts, peptic ulcer disease, hyponatremia, bleeding problems, and glaucoma. Because of certain drug interactions, you should also talk about all supplements, prescription medications, nonprescription medications, and herbal products you are using.
Patients suffering from depression should continually be monitored for risk of suicidal thoughts. Call your suicide hotline once you notice signs of suicide. Changes in sleep patterns, giving away valuables, talking about death, lack of interest, changes in conduct, emotional detachment, and obtaining fatal methods are all warning indications.
Dizziness and vomiting are among the adverse effects of this SSRI. They could worsen alcohol consumption. Severe vomiting could lead to hyponatremia or decreased sodium levels, which is among the severe adverse reactions of this drug. Limit your intake of alcoholic drinks while taking Trintellix.
Pregnant women and breastfeeding moms should discuss with their healthcare provider the possible risks and benefits of this antidepressant. Call your doctor once you decide to take Trintellix.
Frequently Asked Questions
1. What is Trintellix used for?
This drug is used to treat MDD or major depressive disorder. It’s also used for anxiety off-label.
2. Does Trintellix work right away?
It may take a couple of months (4-8) before you notice the effectiveness of this antidepressant.
3. Which is better, Trintellix vs Zoloft?
These medications for depression are equally effective. While the former is prescribed for adults, the latter can be used by children and adolescents.
4. Does Trintellix make you sleepy?
Drowsiness or tired feeling is not directly related to this oral drug.
5. How much does Trintellix cost?
You may check the pricing of this product by clicking here.