Generic Name: budesonide, glycopyrrolate, and formoterol fumarate
Drug Class: corticosteroid, anticholinergic, and long-acting beta 2-adrenergic agonist
Breztri Aerosphere Indications
Breztri Aerosphere is an oral prescription inhaler used as a maintenance treatment for people with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It prevents and controls symptoms such as wheezing, persistent cough, and shortness of breath.
Breztri Aerosphere Dosage Forms
This is available in Breztri Aerosphere 160 mcg/7.2 mcg/5 mcg inhalation aerosol, which is equivalent to 160/9/5 mcg that is available in the USA.
*The 7.2mcg Glycopyrronium “Bromide” is equivalent to 9mcg Glycopyrrolate, while the 4.8mcg Formoterol Fumarate “Dihydrate” is equivalent to 5mcg Formoterol Fumarate.
Breztri Aerosphere Mechanism of Action
This drug has multiple actions.
First, it acts on multiple cell types and mediators that are responsible for inflammation. Breztri Aerosphere works directly on the lungs to reduce swelling and ease breathing.
Second, it inhibits the M3 receptors of the bronchial smooth muscle, which results in bronchodilation.
Third, it stimulates intracellular adenyl cyclase, which converts adenosine triphosphate to cyclic adenosine monophosphate. Increased levels of cyclic AMP can result in bronchial smooth muscle relaxation and inhibition of the release of immediate hypersensitivity mediators.
How to Use Breztri Aerosphere
Before you use this inhaler, you must read the drug information leaflet or brochure that comes with it. Do not use this oral inhaler unless you thoroughly understand all the information and instructions. Ask your doctor or the pharmacist for further information.
Breztri Aerosphere Inhaler is usually prescribed twice a day, in the morning and the evening. Remember to use the inhaler at the same time each day. Make a dosing schedule so you will not miss your doses. Do not increase/decrease your Breztri Aerosphere dosage or use this inhaler more frequently than prescribed. Avoid using this product if you are using a quick-relief inhaler.
Step by Step Breztri Aerosphere Directions:
- Remove the cap. Then, shake the inhaler well.
- Hold the device in an upright manner with the mouthpiece down and facing you.
- Exhale as fully as you can through your mouth.
- Close the lips around the mouthpiece. Tilt your head back and keep the tongue below the mouthpiece.
- Press down the inhaler while you inhale slowly and deeply. When the canister stops moving, release the dose indicator.
- Remove the inhaler from inside your mouth and hold your breath for 10 secs or more.
- Exhale gently. If you need to take another puff/dose, wait for a minute and repeat steps 1-7.
- Once finished, replace the cap and rinse the mouth.
Breztri Aerosphere Side Effects
Mild & Common Side Effects:
-Dry or irritated throat
Severe Side Effects:
-High blood pressure
-White patches inside the mouth
-Persistent sore throat
Note: This is not a complete or full list of adverse reactions. If any side effects persist or worsen, you must call your doctor or any healthcare professional.
Warnings and Precautions when using Breztri Aerosphere
Do not use this oral inhalation spray if you have an allergy to budesonide, glycopyrrolate, formoterol, arformoterol, or any inactive ingredients it contains. Signs of serious allergic reactions are severe dizziness, skin rashes, swelling of the face and neck, hives, swollen lymph nodes, and trouble breathing. This must be considered a medical emergency. Immediately call for emergency help if this happens.
This prescription drug may be contraindicated for people with a history of any recent infections, heart problems, eye problems, hyperthyroidism, hypertension, diabetes, osteoporosis, enlarged prostate, and liver disease. Due to possible drug interactions, it is also important to talk about all the prescription drugs, OTC drugs, supplements, and herbal products you are taking.
This inhaler can cause QT prolongation, which could be considered a medical emergency. Symptoms are severe dizziness and fainting. Stay hydrated and avoid water pills to prevent this. You should also be monitored for low magnesium and potassium levels in the blood, as they may also lead to QT prolongation.
The use of steroids can weaken the body’s defense system. There is a possibility that taking this drug may mask the symptoms of infection or make you more likely to get one. Avoid coming in contact with people who have recent infections, such as the flu, chickenpox, or measles.
The possible risks and effects of this product on unborn babies and breastfed infants should be discussed with your doctor if you are pregnant or breastfeeding.
How much does Breztri Aerosphere cost in Canada?
Check the top of this page to see how affordable and reasonable our prices are for its effectiveness.
Frequently Asked Questions (FAQs)
What is Breztri Aerosphere inhaler used for?
Breztri Aerosphere is an inhalation aerosol that is primarily used to manage symptoms of COPD. It is also used to prevent breathing symptoms. This is used as a maintenance treatment.
Is Breztri Aerosphere a steroid?
Breztri Aerosphere contains an inhaled corticosteroid in the form of budesonide. Other active components of this drug are anticholinergic and LABA.
Can I use Breztri Aerosphere for asthma attacks?
This inhaler is not indicated to relieve sudden breathing problems. You should use a separate quick-relief inhaler for acute bronchospasm.
Is Breztri Aerosphere the same as Symbicort?
Both medications contain budesonide and formoterol. However, unlike Symbicort, Breztri Aerosphere has glycopyrrolate.
Is Breztri Aerosphere over the counter?
You cannot purchase this inhalation aerosol over the counter. You can only buy this product by prescription.
Where can I buy Breztri Aerosphere?
If you are buying drugs online, make sure to buy from legitimate sources. You may purchase this oral inhaler from our online pharmacy like ours.